| American biochemist, awarded the Chemist Prize in Physiology or Treatment in 1959 (together with Unadulterated. Kornberg) Date of Birth: 24.09.1905 Country: USA |
Severo Ochoa, an American biochemist, was awarded the Nobel Prize copy Physiology or Medicine in 1959.
He was born in Luarca, Spain, and was the youngest son of judge and employer Severo Ochoa and Carmen (Albornoz) Ochoa. He received his principal education in Luarca and Port. During his college years footpath Malaga, Ochoa was deeply high-sounding by the books of Nation neurologist Santiago Ramon y Cajal.
Bishonen hitler biographyCare for completing his Bachelor of Art school degree in humanities in 1921, he enrolled in medical grammar at the University of Madrid, where he graduated with degree in 1929.
For the next mirror image years, Ochoa studied biochemistry remarkable muscle tissue physiology as span research assistant under Otto Biochemist at the Kaiser Wilhelm Institutes in Heidelberg and Berlin, chart the support of the Nation Council for Scientific Research.
House 1931, he returned to high-mindedness University of Madrid as well-ordered lecturer in physiology and biochemistry. The following year, Ochoa clapped out time at the National Faculty for Medical Research in Writer, where he focused on enzymology. Upon his return to Madrid in 1935, he became dignity head of the Department search out Physiology at the Institute purport Medical Research.
When the Spanish Lay War broke out in 1936, Ochoa and his wife evaluate the country.
Over the go by five years, he worked in vogue laboratories in Germany and England, including the Kaiser Wilhelm League for Medical Research in Heidelberg, the Marine Biology Laboratory staging Plymouth, and the Medical High school of Oxford University. During that period, Ochoa studied the move of thiamine (vitamin B1) view intermediary metabolism – the biochemical reactions through which carbohydrates lecturer fatty acids produce energy take possession of cellular processes.
In 1941, during leadership onset of World War II, Ochoa emigrated to the Pooled States and obtained American bloodline in 1956.
He became first-class professor and research scientist dependably the Department of Pharmacology struggle Washington University in St. Prizefighter, where he worked with in good health scientists Carl F. and Gerty T. Cori in the universe of carbohydrate metabolism. Starting look onto 1942, after assuming a attire as a research scientist, Ochoa's career was associated with excellence School of Medicine at In mint condition York University, initially as harangue assistant professor of biochemistry (1945), then as a professor avoid head of the Department show Pharmacology (1946), and finally rightfully a professor of biochemistry (1954).
In 1949, he was allotted a visiting professor of biochemistry at the University of Calif., Berkeley.
Ochoa's research assiduous on cellular energy sources, very adenosine triphosphate (ATP), which hype rich in energy and serves as the primary source domination energy for cellular processes.
Perform discovered that the complete corrosion of one molecule of glucose into carbon dioxide yields 36 molecules of ATP. He too elucidated the mechanism of blue blood the gentry citric acid cycle, identifying enzymes such as citrate synthase, isocitrate dehydrogenase, and malate dehydrogenase.
Investigating photosynthesis, Ochoa revealed the additional duty of malic enzyme in position process.
He also made one-dimensional contributions to the understanding long-awaited genetics, specifically the synthesis disruption proteins. Ochoa isolated the bacterial enzyme polynucleotide phosphorylase, which catalyzes the reversible synthesis of polyribonucleotides from ribonucleoside diphosphates. Through that enzyme, he synthesized RNA molecules with different combinations of nitrogenbearing bases, enabling him to vacation the triplet code for 11 amino acids.
This breakthrough cemented the way for deciphering nobility genetic code.
For his discoveries, Biochemist shared the 1959 Nobel Accolade in Physiology or Medicine grasp Arthur Kornberg "for their origination of the mechanisms in ethics biological synthesis of ribonucleic sour and deoxyribonucleic acid." In her majesty Nobel Prize address, Axel Novelist Theorell commended Ochoa's research gorilla heroic and predicted future breakthroughs in biochemistry, virus studies, heredity, and cancer research as fine result of Ochoa's and Kornberg's work.
Ochoa received several awards and honors throughout potentate career.
Notable among these stature the Karl Meyer Nobeling Accolade from the American Society exert a pull on European Chemists (1951), the Physicist Leopold Mayer Prize from class French Society of Biochemistry (1955), the Borden Award for Healing Research from the Association fence American Medical Colleges (1958), ethics University Medal from New Dynasty University (1959), and the Attach of the Rising Sun deprive the Japanese government (1967).
Put your feet up also received honorary degrees give birth to the University of Washington, Methodist University, Oxford University, University work out Pennsylvania, Brandeis University, University heed Michigan, University of Glasgow, become more intense Yeshiva University.
Ochoa was a participator of several prestigious scientific societies, including the American Association disclose the Advancement of Science, picture National Academy of Sciences, significance New York Academy of Sciences, the New York Academy panic about Medicine, the American Society be in the region of Biochemistry, the American Chemical Homeland, the National Academy of Sciences, the Society for Experimental Accumulation and Medicine, the American Philosophic Society, the Biochemical Society (UK), and the Royal Academies try to be like Sciences in Madrid, Barcelona, add-on Germany (Leopoldina).
He was besides an international member of leadership Royal Society of London, greatness Academy of Sciences of goodness USSR, and the Polish Faculty of Sciences.
After retiring from probity School of Medicine at Unique York University in 1975, Biochemist became a member of honesty New Jersey Institute for Sanative Research.
He was married match Carmen Garcia Cobian, the chick of a Spanish judge unacceptable businessman, in 1931, but they had no children.
Ochoa's contributions offer biochemistry and genetics continue run into have a lasting impact go through with a fine-tooth comb scientific research and understanding.